Coffee found to
reduce malignant melanoma risk
Both
epidemiological and pre-clinical studies have suggested that coffee consumption
has a protective effect against non-melanoma skin cancers.
However the
protective effect for cutaneous melanoma (malignant and in situ) is less clear,
according to a study published January 20 in the JNCI: Journal of the
National Cancer Institute.
To
determine if there is an association between coffee consumption and risk of
cutaneous melanoma, Erikka Loftfield, M.P.H., of the Division of Cancer
Epidemiology and Genetics, National Cancer Institute, and colleagues used data
from the NIH-AARP Diet and Health Study. Information on coffee consumption was
obtained from 447,357 non-Hispanic white subjects with a self-administered
food-frequency questionnaire in 1995/1996, with a median follow-up of 10 years.
Overall,
the highest coffee intake was inversely associated with a risk of malignant
melanoma, with a 20% lower risk for those who consumed 4 cups per day or more.
There was also a trend toward more protection with higher intake, with the
protective effect increasing from 1 or fewer cups to 4 or more.
However, the
effect was statistically significant for caffeinated but not decaffeinated
coffee and only for protection against malignant melanoma but not melanoma
in-situ, which may have a different etiology.
Read
more at EurekAlert.