Kyoto University
Japan's favorite beverage might be offering more than just a
relaxing tea break.
According to new research, green tea could prevent a deadly
condition in the body's main artery. A Kyoto University team has found that
abdominal aortic aneurysm -- a condition in which the main artery becomes
overstretched and bloated -- developed less frequently in rats that drank green
tea polyphenol, a major component of green tea.
Without treatment, abdominal aortic aneurysms eventually rupture
and lead to death 50% of the time.
"Abdominal aortic aneurysms often go unnoticed because there are no symptoms until they burst," says Kenji Minakata, an author of the study.
"If a patient is lucky and bloating is found before
rupture, it needs to be treated surgically, such as by transplanting an
artificial blood vessel or inserting a stent graft. At the moment there are no
pharmacological treatments."
Recent research has pointed to a host of health benefits from
drinking green tea, including the prevention of cancer, cardiovascular disease,
inflammation, and oxidation.
"The type of polyphenol found in green tea has recently
been shown to regenerate elastin, an essential protein that gives the artery
its stretchy, yet study, texture," explains lead author Shuji Setozaki.
"Considering that abdominal arterial aneurysms are caused
by inflammation and the degradation of elastin components in the arterial wall,
we thought drinking green tea may show promise for treatment."
In the study, the team treated rats with enzymes that induce
abdominal aortic aneurysm, and found that the condition developed less in rats
that drank green tea polyphenol. They also saw less inflammation and more
elastin production, protecting the artery from rupture.
"Japanese people have the longest lifespan in the world,
and studies show that 80% of the population drink green tea on a daily
basis," says co-author Hidetoshi Masumoto.
"We believe daily intake of green tea should be considered
as a new preventative strategy for abdominal aortic aneurysm; the focus of future
studies will be to investigate optimal doses."