University of Chicago infectious disease expert answers common questions about Monkeypox.
By UNIVERSITY OF CHICAGO
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| The global investigation into the 2022 monkeypox outbreak is still in its early stages and public health teams are learning more each day as case counts grow. |
Scientists at the Centers for Disease Control and Prevention (CDC) are tracking cases of monkeypox that have been reported in numerous countries that do not normally have the disease, including the United States.
This new monkeypox outbreak is making headlines about this rare, transmissible virus that’s related to smallpox. The global investigation into the 2022 outbreak—which differs from previous clusters of monkeypox—is still in its early stages and public health teams are learning more each day as case counts grow.
Emily Landon specializes in infectious disease and serves as executive medical director for infection prevention and control at the University of Chicago Medicine. She writes:
“It’s important to know that the risk of acquiring monkeypox through casual contact is extremely low at this time. And our best COVID-19 safety practices like masks and regular hand washing will be incredibly important tools to help protect us against monkeypox.
Similarly, it’s critical that anyone who’s been exposed to monkeypox or who thinks they may have symptoms isolates and notifies public health authorities immediately. This situation is evolving quickly and our information is based on the understanding of this outbreak at the time of this post’s publication. We’ll likely know much more in the weeks and months to come. But for now, here’s what we think you should know about monkeypox and how you can stay safe.”
What is monkeypox?
Monkeypox
is a zoonotic infection, which means it began in animals and was transmitted to
humans. It’s endemic to Africa and transmitted when someone has close contact
with another monkeypox patient or from rodents carrying the disease. Contrary
to its namesake, monkeys aren’t reservoirs or common hosts of monkeypox. In
fact, the virus is most often traced to rodents. It’s from the same family as
other poxviruses including smallpox (called orthopoxviridae) and was first
discovered in humans in 1970.
What does monkeypox look like? Are there other symptoms?
A
monkeypox rash starts as red spots and progresses over time to pus-filled,
blister-like lesions that eventually scab over. It is typically found on the
face or extremities like the hands, legs and feet. The lesions are generally
all the same size and develop at the same rate. In the latest round of cases,
many of the patients had the rash on only the genitals or anus, which means the
symptoms may be mistaken for a sexually transmitted infection or STI.
Sometimes a person with monkeypox will feel like they’re coming down with a cold or flu days before their rash develops. These symptoms include headaches, fevers, muscle and body aches, and fatigue. They may also have swollen lymph nodes.
How does monkeypox spread?
Monkeypox
is spread through direct skin-to-skin contact with the monkeypox lesions or the
fluid inside them. The virus can also be spread by breathing in or directly
contacting infected respiratory droplets. There have been some cases where
monkeypox was transmitted from surfaces that were contaminated with respiratory
droplets or fluid from the lesions. (This is another reason we need to keep
wearing the masks we’ve been accustomed to during the COVID-19 pandemic and why
we should keep washing our hands regularly and cleaning high-touch surfaces.)
How long does it take to become sick?
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| Monkeypox belongs to the Poxviridae family of viruses, which includes smallpox. Credit: CDC |
The good news: A long incubation period means we can give people treatments or vaccines that can help keep them from getting sick if we’re able to catch it early. That makes it important to contact your doctor or the health department right away if you may have been exposed to monkeypox. The entire illness lasts about two to four weeks.
How dangerous is monkeypox?
This
outbreak involves what’s known as the western African clade, which is less
severe and has a fatality rate of about 1%. But many of those cases have
occurred in countries where there weren’t many medical resources, which means
people likely had worse outcomes than they would have in other regions of the
world. No one has died from monkeypox in the U.S. during previous outbreaks.
How is monkeypox treated?
Since
monkeypox and smallpox are related, we can use the smallpox vaccine to prevent
illness even after someone has been exposed. It’s about 85% protective against
monkeypox. (However, someone’s immunity can weaken as they age.) There is also
a new vaccine that can be used, but it is in short supply. Antiviral
medications, such as cidofovir or tecovirimat, can be used to treat severe
cases. Some people may also be treated with immune globulin antibodies if they
can’t get other kinds of treatment. Most people don’t require any treatment and
get over the infection on their own.
Who is most at risk for monkeypox?
Unlike
previous outbreaks, some of the people who are currently being infected with
monkeypox are people who identify as men who’ve had sexual contact with men and
reported new partners in the last month. However, cases aren’t limited to one sex
or sexual orientation, and there are reports of household contacts being
infected. This makes it challenging to diagnose monkeypox because doctors may
mistake skin lesions for more common infections. There’s good reason to believe
other cases may have gone undiagnosed.
As of June 10, 2022, the CDC is reporting 1472 confirmed monkeypox cases in 33 non-endemic countries. The list includes (in order of most cases to least cases): United Kingdom, United Kingdom, Spain, Portugal, Germany, Canada, France, Netherlands, United States, Italy, Belgium, Switzerland, United Arab Emirates, Ireland, Australia, Czechia, Slovenia, Sweden, Denmark, Israel, Finland, Argentina, Iceland, Latvia, Norway, Austria, Brazil, Gibraltar, Greece, Hungary, Malta, Mexico, Morocco, and Poland.