New medical evidence shows consuming cranberry products is an effective way to prevent a UTI
Flinders University
Drinking cranberry juice has long been a mythical prevention strategy for women who develop a urinary tract infection -- and new medical evidence shows consuming cranberry products is an effective way to prevent a UTI before it gets started.
A global study looking at the benefits of cranberry products published
in Cochrane Reviews has determined cranberry juice, and its
supplements, reduce the risk of repeat symptomatic UTIs in women by more than a
quarter, in children by more than half, and in people susceptible to UTI
following medical interventions by about 53%.
Cranberry juice and healthcare supplements that commonly include the
fruit, such as capsules and tablets, have long been promoted as a readily
available solution to ward off the infection but the most recent review in
2012, with evidence from 24 trials, showed no benefit from the products.
The medical scientists behind this updated review from Flinders University and The Children's Hospital at Westmead aimed to update these findings, as an important step in determining the effectiveness of cranberry products by looking at 50 more recent trials that included almost 9000 participants.
"This incredible result didn't really surprise us, as we're taught
that when there's more and better evidence, the truth will ultimately come out.
UTIs are horrible and very common; about a third of women will experience one,
as will many elderly people and also people with bladder issues from spinal
cord injury or other conditions," says the study lead author Dr. Gabrielle
Williams.
"Even back in 1973, my mum was told to try cranberry juice to prevent
her horrible and frequent UTIs, and for her it's been a saviour. Despite me
niggling in her ear about evidence, she's continued to take it daily, first as
the nasty sour juice and in recent years, the easy to swallow capsules. As soon
as she stops, wham the symptoms are back. As usual, it turns out that mum was
right! Cranberry products can help some women prevent UTIs."
Flinders University epidemiologist Dr. Jacqueline Stephens, a co-author of
the study, says if the UTI persists untreated it can move to the kidneys and
cause pain and more complications, including sepsis in very severe cases, so
prevention is the most effective way to reduce risks.
"Most UTIs are effectively, and pretty quickly, treated with
antibiotics, sometimes as little as one dose can cure the problem.
Unfortunately, in some people UTIs keep coming back. Without being sure if or
how it works, some healthcare providers began suggesting it to their patients.
It was a harmless, easy option at the time. Even centuries ago, Native
Americans reportedly ate cranberries for bladder problems, leading somewhat
more recently, to laboratory scientists exploring what it was in cranberries
that helped and how it might work."
"The studies we looked at included a range of methods to determine
the benefits of cranberry products. The vast majority compared cranberry
products with a placebo or no treatment for UTI and determined drinking
cranberries as a juice or taking capsules reduced the number of UTIs in women
with recurrent cases, in children and in people susceptible to UTi's following
medical interventions such as bladder radiotherapy."
"It's also important to consider that few people reported any side
effects with the most common being tummy pain based on the results. We also did
not find enough information to determine if cranberry products are more or less
effective compared with antibiotics or probiotics in preventing further
UTIs."
The data also doesn't show any benefit for elderly people, pregnant women
or in people with bladder emptying problems.
Senior Author, Professor Jonathan Craig, Vice President and Executive Dean
of the College of Medicine & Public Health at Flinders University, says the
real benefits of cranberry products became clear when the researchers expanded
the scope of the review to include the most recently available clinical data.
"This is a review of the totality of the evidence and as new evidence
emerges, new findings might occur. In this case, the new evidence shows a very
positive finding that cranberry juice can prevent UTI in susceptible
people," says Professor Craig.
"We have shown the efficacy of cranberry products for the treatment
of UTIs using all the evidence published on this topic since the mid-nineties.
The earlier versions of this review didn't have enough evidence to determine
efficacy and subsequent clinical trials showed varied results, but in this
updated review the volume of data has shown this new finding."
The study authors conclude that while cranberry products do help prevent UTIs in women with frequent recurrence, more studies are needed to further clarify who with UTI would benefit most from cranberry products.